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PAK6-knockdown cells exhibit a greater degree of apoptosis compared to control cells following irradiation. (a) Annexin V Assay comparing the percentage of apoptotic cells in PAK6-deficient PC3 cells with control cells 72 hours following 6 Gy irradiation. (b) Cleaved PARP and cleaved caspase-3 levels in control and PAK6-knockdown PC3 cells at 24 and 48 hours following 6 Gy irradiation.
