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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Cell Signal. 2010 Mar 3;22(7):1076–1087. doi: 10.1016/j.cellsig.2010.02.010

Fig. 5.

Fig. 5

Effects of suppression of IGF-R1-mediated signaling pathway on AKT and ERK activation and apoptosis of HSF. (A) Western blot analysis of indicated proteins from HSF, which were irradiated in the presence and absence of PPP (0.5 μM). Actin was used as a protein loading control. (B) G2/M arrest of the cell cycle following PPP (0.25–1.0 μM) treatment of HSF. (C) Clonogenic survival assay of HSF 12 days after indicated treatment with PPP.