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Mitochondrial production rates of (A) ROS, (B) superoxide, and (C) hydrogen peroxide, as determined by EPR, were significantly higher in db/db mice than in any other group. PDTC treatment normalized production rates of ROS, superoxide, and hydrogen peroxide in isolated LV mitochondria. *P < 0.05 vs. control; #P < 0.05 vs. db/db; $P < 0.05 vs. db/db PDTC; @P < 0.05 vs. hz PDTC.
