Table 1. Selected characteristics of subjects by case-control status.
| Controls | Biliary Tract Cancers | Biliary Stones3 | ||||
|---|---|---|---|---|---|---|
| Selected Characteristics | Gallbladder1 | Bile duct2 | Ampulla of Vater2 |
Gallbladder | Bile duct | |
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |
| Total | 786(100.0) | 236(100.0) | 127(100.0) | 47(100.0) | 670(100.0) | 221(100.0) |
| Sex | ||||||
| Male | 305 (38.8) |
65 (27.4) | 76 (59.8) | 24 (51.1) | 223 (33.3) | 104 (47.1) |
| Female | 481 (61.2) |
172 (72.6)* | 51 (40.2)* | 23 (48.9) | 447 (66.7)* | 117 (52.9) |
| Age at interview (years) | ||||||
| <54 | 107 (13.6) |
32 (13.5) | 18 (14.2) | 4 (8.5) | 213 (31.8) | 53 (24.0) |
| 55-64 | 224 (28.5) |
62 (26.2) | 32 (25.2) | 9 (19.2) | 196 (27.8) | 66 (29.9) |
| >=65 | 455 (57.9) |
143 (60.3) | 77 (60.6) | 34 (72.3) | 271 (40.4)* | 102 (46.1)* |
| Body Mass Index4 (kg/m2) | ||||||
| < 18.5 | 66 (8.4) |
11 (4.7) | 6 (4.7) | 1 (2.1) | 15 (6.8) | 2 (2.7) |
| 18.5-22.9 | 325 (41.4) |
79 (33.5) | 57 (44.9) | 20 (42.6) | 74 (33.5) | 31 (41.9) |
| 23.0-24.9 | 166 (21.2) |
47 (19.9) | 33 (26.0) | 11 (23.4) | 51 (23.1) | 15 (20.3) |
| >=25.0 | 228 (29.0) |
99 (41.9)* | 31 (24.4) | 15 (3.9) | 81 (36.6)* | 26 (35.1)* |
|
Ever smoke cigarettes
regularly 5 |
||||||
| No | 549 (69.9) |
172 (72.9) | 71 (55.9) | 27 (57.5) | 510 (76.1) | 141 (63.8) |
| Yes | 237 (30.2) |
64 (27.1) | 56 (44.1)* | 20 (42.6) | 160 (23.9)* | 80 (36.2) |
|
Ever drink alcohol
regularly |
||||||
| No | 624 (79.4) |
201 (84.8) | 85 (66.9) | 35 (74.5) | 569 (84.9) | 180 (81.8) |
| Yes | 162 (39.2) |
36 (15.2) | 42 (33.1)* | 12 (25.5) | 101 (15.1)* | 40 (18.2) |
| Gallstone Status | ||||||
| No | 592 (75.3) |
36 (15.2) | 41 (32.3) | 19 (40.4) | - | - |
| Yes | 194 (24.7) |
201 (84.8)* | 86 (67.7)* | 28 (59.6)* | 670(100.0) | 221(100.0) |
Note: Total number of subjects in some columns may vary across variables because of missing values.
1
Gallbladder cancer cases compared with controls with a gallbladder (n=737).
2
Bile duct and ampulla of Vater cancer cases compared with all controls (n=786).
3
Biliary stone cases compared with controls without stones (n=592).
4
Body Mass Index (BMI) = weight/height2. Categories based on WHO classification for Asians.
5
Ever smoked cigarettes consecutively for at least 6 months.
*
p <0.05 chi-square test for difference between cases and controls.