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. Author manuscript; available in PMC: 2010 Apr 28.
Published in final edited form as: Mol Psychiatry. 2009 Feb 10;14(11):1004–1016. doi: 10.1038/mp.2009.10

Table 2.

Association between the SNPs and the risk of developing AD in the French and American sub-populations

French
 American
 French + American
SNP OR [95% C.I.] Pa OR [95% C.I.] Pa OR [95% C.I.] Pb
Tag-SNP* rs7848215 1.4 [0.9–2.0] 0.11 1.5 [1.0–2.3] 0.06 1.4 [1.1–1.9] 0.01
rs16924144 0.9 [0.6–1.4] 0.77 0.7 [0.5–1.2] 0.19 0.8 [0.6–1.1] 0.28
rs16924159 0.9 [0.6–1.3] 0.58 0.6 [0.4–1.0] 0.05 0.8 [0.6–1.0] 0.08
rs7044343 0.5 [0.3–0.7] 2.10−4 0.6 [0.4–1.0] 0.05 0.5 [0.4–0.7] 3.10−5
Supplementary SNPs rs1157505 0.6 [0.4–0.9] 0.008 0.6 [0.4–0.9] 0.03 0.6 [0.4–0.8] 6.10−4
rs1891385 0.9 [0.5–1.4] 0.62 1.5 [0.9–2.5] 0.16 1.1 [0.8–1.6] 0.58
rs996029 0.7 [0.4–1.4] 0.36 1.4 [0.6–3.1] 0.38 0.9 [0.5–1.6] 0.79
rs16924161 0.8 [0.5–1.3] 0.48 0.9 [0.5–1.4] 0.52 0.9 [0.6–1.2] 0.35
rs10975511 0.8 [0.6–1.2] 0.36 0.7 [0.4–1.1] 0.09 0.8 [0.6–1.0] 0.06
rs7035413 1.3 [0.9–1.9] 0.20 1.7 [1.1–2.6] 0.02 1.4 [1.1–1.9] 0.01
rs11792633 0.5 [0.3–0.7] 5.10−4 0.8 [0.5–1.2] 0.23 0.6 [0.4–0.8] 6.10−4
rs8172 0.8 [0.4–1.3] 0.32 0.7 [0.4–1.3] 0.25 0.7 [0.5–1.1] 0.12
a

adjusted for age, sex and APOE status

b

adjusted for age, sex, APOE status and centre

*

TagSNPs selected in HapMap database