. 2010 Feb 13;19(10):1883–1896. doi: 10.1093/hmg/ddq064

Table 1.

List of fly genotypes used in this study and their abbreviations

Abbreviation	Genotype
WCS (Control)	Canton S, w⁻
Ø,Ø (Null)	w; +/CyOKrGFP; elav-GS-Gal4, spastin^5.75/spastin^5.75
D^WT,Ø	w; UAS-CFP-Dspastin/+; elav-GS-Gal4, spastin^5.75/spastin^5.75
H^WT,Ø	w; UAS-Venus-Hspastin^WT/+; elav-GS-Gal4, spastin^5.75/spastin^5.75
H^L44,Ø	w; UAS-CFP-Hspastin^L44/+; elav-GS-Gal4, spastin^5.75/spastin^5.75
H^R388,Ø	w; UAS-Venus-Hspastin^R388/+; elav-GS-Gal4, spastin^5.75/spastin^5.75
H^WT,H^WT (Wild-Type)	w; UAS-Venus-Hspastin^WT, UAS-Venus-Hspastin^WT/+; elav-GS-Gal4, spastin^5.75/spastin^5.75
H^WT,H^L44 (S44L Heterozygote)	w; UAS-Venus-Hspastin^WT, UAS-CFP-Hspastin^L44/+; elav-GS-Gal4, spastin^5.75/spastin^5.75
H^WT,H^R388 (K388R Heterozygote)	w; UAS-Venus-Hspastin^WT, UAS-Venus-Hspastin^R388/+; elav-GS-Gal4, spastin^5.75/spastin^5.75
H^L44,H^R388 (S44L, K388R Compound Het)	w; UAS-CFP-Hspastin^L44, UAS-Venus-Hspastin^R388/+; elav-GS-Gal4,spastin^5.75/spastin^5.75

Canton S, w⁻, the control genotype, is a wild-type Drosophila strain that has been backcrossed to white⁻ ten times (39); spastin^5.75 is the Drosophila spastin null allele (25). Additional genotypes were analyzed in which H^Q45 was substituted for H^L44, and H^R431STOP for H^R388. D denotes Drosophila transgenes; H, human transgenes.