Figure 15. Accelerated food transit and increased feces production in Ngn3^Δint mice.

(A) Age- and sex-matched mutant and control mice were fasted overnight and given then simultaneously access to colored food. The time of the appearance of the first colored stool was then taken and normalized to their body weight. Mutant mice have a 2.3-fold accelerated intestinal food transit. (B) The feces of control and mutant mice were collected after 1 or 4 days, and their weight was taken. Mutant mice show an up to 2-fold increase in feces production compared with control mice. (A and B) n = 4–5. **P < 0.01, ***P < 0.001.