Table 1. EC50, CC50 and selectivity index (SI) for monomers, dimers and GCV.
Compound | CC50 (µM) | EC50 (µM) | Selectivity index (SI) |
Dimer sulfone carbamate (6) | 28.1±9.6 | 0.06±0.00 | 508±173 |
Dimer primary alcohol (4) | 57±2.3 | 0.15±0.02 | 380±53 |
GCV | 247±33.4 | 5.6±0.2 | 44±6.2 |
Artemisinin (1) | 72.4±15.7 | 16.8±4.0 | 4.3±1.4 |
Artesunate (2d) | 77.5±14.4 | 18.5±5.2 | 4.2±2.2 |
Artemether (2c) | 18.4±7.5 | 5.3±2.7 | 3.5±2.2 |
Artefanilide (3) | 44.9±3.4 | 8.1±2.2 | 5.5±1.6 |