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. 2010 Apr 28;5(4):e10370. doi: 10.1371/journal.pone.0010370

Table 1. EC50, CC50 and selectivity index (SI) for monomers, dimers and GCV.

Compound CC50 (µM) EC50 (µM) Selectivity index (SI)
Dimer sulfone carbamate (6) 28.1±9.6 0.06±0.00 508±173
Dimer primary alcohol (4) 57±2.3 0.15±0.02 380±53
GCV 247±33.4 5.6±0.2 44±6.2
Artemisinin (1) 72.4±15.7 16.8±4.0 4.3±1.4
Artesunate (2d) 77.5±14.4 18.5±5.2 4.2±2.2
Artemether (2c) 18.4±7.5 5.3±2.7 3.5±2.2
Artefanilide (3) 44.9±3.4 8.1±2.2 5.5±1.6