Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Mar 24;10:9. doi: 10.1186/1475-2867-10-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright ©2010 Tan et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Dz13 inhibits OS metastasis from the bone efficaciously. Dz13 efficacy was next tested in the SaOS-2 orthotopic model. Dz13 was able to reduce OS metastasis to the lung after treatment was administered when tumours were palpable. Both macrometastasis (A) and micrometastasis (B) counts were reduced in the Dz13 cohort. (C) Histology confirmed that there were less micrometastases in lungs of mice in the Dz13 cohort (middle) compared to untreated (top) and Scr-treated (bottom). (D) Primary tumour was not affected by the treatments administered.