Table 3.
Comparison of Patients with and without AAA Undergoing Circulating Cytokine Measurements
| Characteristic | <30 mm | 30–39 mm | ≥40 mm | P value |
|---|---|---|---|---|
| Number | 713 | 245 | 70 | |
| Aortic diameter (mm) | 21.9 (20.2–23.1) | 32.5 (31.0–34.6) | 45.0 (42.1–49.4) | <0.01 |
| Age (years) | 70.6 (68.0–74.2) | 72.2 (68.9–75.2) | 71.1 (68.6–74.7) | <0.01 |
| Hypertension | 276 (39%) | 124 (51%) | 37 (53%) | <0.01 |
| Diabetes mellitus | 49 (7%) | 22 (9%) | 9 (13%) | 0.15 |
| Dyslipidaemia | 263 (37%) | 127 (52%) | 28 (40%) | <0.01 |
| Ever smoker | 449 (63%) | 206 (84%) | 61 (87%) | <0.01 |
| CHD | 123 (17%) | 87 (36%) | 30 (43%) | <0.01 |
| WHR | 0.95 (0.91−0.99) | 0.96 (0.93–1.01) | 0.98 (0.93–1.05) | <0.01 |
| CCL22 (ng/ml) | 0.56 (0.45−0.70) | 0.67 (0.52−0.82) | 0.74 (0.56−0.89) | <0.01 |
| IL-6 (pg/ml) | 14.2 (5.2–38.8) | 9.3 (5.2–31.2) | 17.3 (4.6–38.7) | 0.34 |
| CRP (mg/L) | 1.77 (0.95–3.57) | 2.54 (1.24–5.11) | 2.75 (1.43–5.56) | <0.01 |
| Creatinine (μM) | 89 (78–100) | 92 (80–111) | 103 (90–134) | <0.01 |
Data are shown comparing subjects without AAAs (<30 mm), with small AAAs (30 to 40 mm) and larger AAAs (≥40 mm). Nominal variables are presented as numbers (%) and compared by chi-square. Continuous variables are presented as median (inter-quartile range) and compared by Kruskal Wallis test. CHD = Coronary heart disease; WHR = Waist to hip ratio.