The correlation between serum Angptl2 levels and RA disease activity. A: Correlation of the serum Angptl2 level with DAS28-ESR, DAS28-CRP in RA outpatients (n = 206). B: Serum Angptl2 levels in healthy volunteers (healthy control subjects, n = 84) and in nonactive RA patients characterized by DAS28-CRP remission/DAS28-ESR remission (DAS28-CRP(−)/DAS28-ESR(−), n = 46) patients showing increased RA disease activity characterized by DAS28-CRP remission/DAS28-ESR active (DAS28-CRP(−)/DAS28-ESR(+), n = 44) or DAS28-CRP active/DAS28-ESR active (DAS28-CRP(+)/DAS28-ESR(+), n = 116). Horizontal bars represent the 10th and 90th percentile range, and boxes indicate the 25th to 75th percentile range. The horizontal line in each box corresponds to the median. *P < 0.05 versus healthy control subjects.