Figure 1.

Autophagy in human tissues. Cytoplasmic, perinuclear, and stone-like patterns in malignant breast (A), colonic (B), endometrial (C), and prostatic (D) tissues stained for LC3A. The corresponding negative control sections (E–H) in the preparation of which the LC3A antibody had been replaced by normal rabbit immunoglobulin-G (Magnification ×200). Arrows in B, C, and D show stone-like structures and perinuclear staining of LC3A, whereas those in F, G, and H indicate the corresponding areas in control sections.