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. 2010 May;176(5):2477–2489. doi: 10.2353/ajpath.2010.090049

Table 2.

The Relationship of Diffuse Cytoplasmic Pattern with Certain Histopathological and Immunohistochemical Features in Operable Breast Carcinomas

Parameter Low, n (%) (72 cases) High, n (%) (30 cases) P value
Tumor size
 <1 8 (11.1) 6 (20.0)
 1 to 1.5 22 (30.6) 12 (40.0) 0.20
 1.6 to 2.0 42 (58.3) 12 (40.0)
Number of positive nodes
 0 32 (44.5) 8 (26.7)
 1 to 3 16 (22.2) 16 (53.3) 0.008
 >3 24 (33.3) 6 (20.0)
Tumor grade
 1 to 2 20 (27.8) 14 (46.7) 0.10
 3 52 (72.2) 16 (53.3)
ER
 Negative 34 (47.2) 4 (13.3) 0.001
 Positive 38 (52.8) 26 (86.7)
PgR
 Negative 40 (55.5) 10 (33.3) 0.05
 Positive 32 (44.5) 20 (60.7)
c-erbB-2
 Negative 32 (44.4) 16 (53.3) 0.51
 Positive 40 (55.6) 14 (46.7)

P values: 0 versus 1 to 3 = 0.01; 1 to 3 versus >3 = 0.01; 0 versus >3 = 0.99. 

Negative versus positive = 0.12.