Table 3.

Brain areas showing activation during presentation of the dissociation-inducing script compared with the neutral script and significant correlations between blood oxygen level–dependent signal and dissociation

Group; MNI coordinates			Side	Lobe	Gyrus	BA	T local maximum (voxel level)	κ	1-sample t test*	Correlation between BOLD signal and DSS-4†
BPD, n = 15
−60	6	24	L	Frontal	Inferior frontal	9	5.64	39	DIS > neutral
52	34	32	R	Frontal	Middle frontal	46	4.58	20	Neutral > DIS
−8	−6	70	L	Frontal	Superior frontal	6	4.97	83		Positive
38	−2	−38	R	Temporal	Middle temporal	21	5.02	46		Negative
46	−6	−36	R	Temporal	Inferior temporal	20	4.74	46		Negative
BPD and PTSD, n = 10
−16	−6	68	L	Frontal	Superior frontal	6	6.30	24	DIS > neutral
44	−18	4	R		Insula	13	5.79	38	DIS > neutral
−58	4	24	L	Frontal	Inferior frontal	9	5.31	11	DIS > neutral
−42	−16	46	L	Frontal	Precentral	4	4.94	10	DIS > neutral
−58	−22	16	L	Parietal	Postcentral	40	4.78	16	DIS > neutral
−8	12	38	L	Frontal	Cingulate	32	4.81	10	DIS > neutral
−8	−6	66	L	Frontal	Medial frontal	6	7.40	29		Positive
64	−2	8	R	Temporal	Superior temporal	22	7.39	44		Positive
−42	10	8	L	Frontal	Precentral	44	6.36	60		Positive
−40	4	2	L		Insula	13	5.38	60		Positive
42	−34	18	R		Insula	13	5.52	11		Positive
−38	28	4	L	Frontal	Inferior frontal	47	4.95	13		Positive
28	−12	−30	R	Limbic	Parahippocampal	35	4.83	11		Negative
50	−4	−36	R	Temporal	Inferior temporal	20	8.52	35		Negative

BA = Brodmann area; BOLD = blood oxygen level–dependent; BPD = bipolar disorder; DIS = dissociation-inducing script; DSS-4 = Dissociation Tension Scale-acute;²⁵ L = left; MNI = Montreal Neurological Institute; PTSD = posttraumatic stress disorder; R = right.

^*All p ≤ 0.001

^†Regression analyses.