Fig. 3. Expression of β1- and α2C-adrenoceptors in the striatum.
Double immunostaining of striatal tissues with (A) DARPP-32 and β1-adrenoceptor antibodies and (B) DARPP-32 and α2C-adrenoceptor antibodies. The expression of β1- and α2C-adrenoceptors was detected in many DARPP-32-positive neurons, suggesting their expression both in striatonigral and striatopallidal neurons. In agreement with Pisani et al. (Pisani et al. 2003), the expression of β1-adrenoceptors was also detected in DARPP-32-negative, large-sized neurons (A; arrows), presumably cholinergic interneurons. Scale bars, 10 μm.