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. 2010 Mar 4;37(2):157–177. doi: 10.1007/s10928-010-9151-7

Table 1.

Parameter values used for the simulations with the simple circular/proliferative system model

Parameter Parameter description Value CVa (%)
km Production rate (h−1) 0.5
kd Death rate (h−1) 0.1
R 0 Basic reproductive ratio 5 30
IC50 Plasma concentration of inhibitor giving 50% inhibition (ng/ml) 10 30
RMIC Reproduction minimum inhibitory concentration (ng/ml) 40

aCoefficient of variation