Table 2.
Parameter values used for the simulations with the viral dynamic model
| Parameter | Parameter description | Mean |
|---|---|---|
| R 0 | Reproductive ratio before virus infection and treatment | 5.0 |
| b | Uninfected cell activation rate (day−1) | 1.0 |
| d 2 | Actively infected cell death rate (day−1) | 0.693 |
| IC50 | IC50 after in vitro to in vivo scale factor (ng/ml) | 10.0 |
| d 1 | Uninfected cell death rate (day−1) | 0.0060 |
| f 1 | Fraction of infected cells actively versus latently infected | 0.96 |
| d 3 | Latently infected cell death rate (day−1) | 0.0132 |
| a | Rate of conversion from latently to actively infected (day−1) | 0.0370 |
| p/c | Ratio of birth to death rate of virus | 35.4 |