Table 4. Cell cycle distribution of DU-145 cells following treatment.
Cell cycle distribution of DU-145 cells following treatment with NS-398 and ibuprofen. DU-145 cells were treated for 24h and percentages of cells in different cell cycle compartments were determined by flow cytometry. The data represents Average ± SEM of 3 separate experiments.
Treatment | G1 | S | G2M |
---|---|---|---|
DMSO control | 53.3 + 0.9 | 24.2 + 0.1 | 22.2 + 0.9 |
0.01mM NS-398 | 51.9 + 0.6 | 25.5 + 0.4 | 22.4 + 0.5 |
0.1mM NS-398 | 58.7 + 1.7 | 22.2 + 1.4 | 18.6 + 1.0* |
Control | 51.9 + 1.7 | 24.3 + 1.5 | 23.5 + 1.1 |
0.1mM ibuprofen | 50.4 + 1.3 | 25.0 + 1.4* | 24.5 + 0.4 |
1.5mM ibuprofen | 60.4 + 0.9* | 20.5 + 0.8* | 19.1 + 1.3* |
p <0.05