Table 2.

Correlations Among Biomarkers in 100 SCLC Patients

	ERCC1 AQUA nuclear	Topo2α AQUA nuclear	TS (106) AQUA cytoplasm	TS (106) IHC cytoplasm	TS (4H4) IHC cytoplasm	GARFT IHC nuclear	FPGS IHC cytoplasm
RRM1, AQUA Nuclear	r = 0.20 p = 0.05 n = 100	r = 0.56 p < .0001 n = 100	r = 0.12 p = 0.25 n = 87	r = −0.02 p = 0.87 n = 90	r = 0.06 p = 0.58 n = 96	r = 0.01 p = 0.91 n = 94	r = 0.21 p = 0.04 n = 95
ERCC1, AQUA Nuclear	NA	r = 0.16 p = 0.10 n = 100	r = 0.34 p = 0.001 n = 87	r = 0.27 p = 0.01 n = 90	r = 0.27 p = 0.008 n = 96	r = 0.16 p = 0.12 n = 94	r = 0.10 p = 0.35 n = 95
Topo2α, AQUA Nuclear		NA	r = 0.08 p = 0.45 n = 87	r = 0.04 p = 0.71 n = 90	r = 0.11 p = 0.27 n = 96	r = −0.15 p = 0.14 n = 94	r = 0.20 p = 0.05 n = 95
TS (106), AQUA cytoplasm			NA	r = 0.25 p = 0.03 n = 78	r = 0.29 p = 0.009 n = 83	r = 0.22 p = 0.05 n = 82	r = 0.00 p = 0.97 n = 82
TS (106), IHC Cytoplasm				NA	r = 0.82 p <.0001 n = 90	r = 0.23 p = 0.03 n = 90	r = −0.21 p = 0.05 n = 89
TS (4H4), IHC Cytoplasm					NA	r = 0.28 p = 0.007 n = 94	r = −0.16 p = 0.12 n = 95
GARFT, IHC Nuclear						NA	r = −0.02 p = 0.89 n = 93

NOTE: r = Spearman correlation coefficient, p = p-value, n = number of observations.