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. Author manuscript; available in PMC: 2010 Apr 29.
Published in final edited form as: Virology. 2006 Sep 28;358(2):485–492. doi: 10.1016/j.virol.2006.08.044

Fig. 4.

Fig. 4

Dependence of PyV-specific in vivo CTL activity on perforin and Fas. (A) LT359 peptide-pulsed and unpulsed naïve C57BL/6, lpr, or TNFR−/− spleen cells were injected into C57BL/6 mice 7 days after PyV infection. Peptide-pulsed and unpulsed naïve spleen cells were injected into PKO mice 7 days postinfection. Peptide-pulsed and unpulsed lpr spleen cells were injected into PKO mice 7 days postinfection. (B) LT359 peptide-pulsed and unpulsed naïve C57BL/6 spleen cells were injected into C57BL/6 or PKO mice during the acute or persistent phase of the immune response. For both (A) and (B), values represent mean ± SEM percent specific lysis of peptide-pulsed spleen cells at 4 hours of 3 recipient mice in 2 separate experiments.