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. Author manuscript; available in PMC: 2010 Sep 15.
Published in final edited form as: Clin Cancer Res. 2009 Sep 1;15(18):5910–5916. doi: 10.1158/1078-0432.CCR-09-0542

Table 3. Best overall response.

Response, n (%) Nilotinib 400 mg bid
n=18
Nilotinib 200 mg qd/imatinib 400 mg bid
n=7
Nilotinib 400 mg qd/imatinib 400 mg bid
n=7
Nilotinib 400 mg bid/imatinib 400 mg bid
n=5
Nilotinib 400 mg bid/imatinib 400 mg qd
n=16
Complete response 0 0 0 0 0
Partial response 1 (6) 0 0 0 1 (6)
Stable disease 13 (72) 7 (100) 5 (71) 4 (80) 9 (56)
Progressive disease 2 (11) 0 1 (14) 0 6 (38)
Unknown* 1 (6) 0 0 0 0
N/A 1 (6) 0 1 (14) 1 (20) 0

Progression-free survival – Kaplan-Meier estimates
Rate at 4 months, % 59 83 43 50 56
Rate at 6 months, % 47 17 29 50 56
Median, days 168 143 112 Ongoing Ongoing
 Range 1-393 56-223 22-336 1-322 27-180
Median follow-up, days 186 153 113 167 126
*

Best response could not be classified as partial or complete response, progressive or stable disease;

Not assessed: patients had discontinued study prior to the first post-baseline tumor assessment.