A comparison of sequential short axis ex vivo views of a canine heart with areas of necrosis seen with triphenyltetrazolium chloride (TTC) (column left) compared late gadolinium enhancement (LGE) magnetic resonance images (column right). Note the excellent correlation between myocardial necrosis seen with TTC and the presence of scar using LGE imaging. Reproduced with permission from: Kim RJ, Fieno DS, Parrish TB, et al. Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile dysfunction. Circulation 1999;100:1992-2002.