Table 4.
ANCOVAs on the relationships between individual personality factor and ADH1A gene
| Group | Models | Variables (sample sizes, n) | A | C | N |
|---|---|---|---|---|---|
| EA SD | Diplotypewise | TGA/TGA × Female (n=5) | 0.003 | ||
| (n=179) | TGA/TGA (n=11) | 0.004 | |||
| Haplotypewise | TGA × TGA × Female (n=5) | 0.001 | |||
| TGA × TGA (n=11) | 0.055 | ||||
| Genotypewise | SNP1ˆT/T × SNP3ˆA/A × Female (n=5) | 0.002 | |||
| AA SD | Diplotypewise | AGA/TGA × Female (n=5) | 0.018 | 0.031 | |
| (n=68) | Haplotypewise | AGA × TGA × Female (n=5) | 0.018 | 0.031 | |
| Genotypewise | SNP2ˆG/G × SNP3ˆA/A × Female (n=5) | 0.030 | |||
| SNP2ˆG/G × SNP3ˆG/G × Male (n=15) | 0.043 | ||||
| EA controls | Diplotypewise | AGA/TGA × Male (n=26) | 0.014 | 0.019 | |
| (n=285) | TCG/TCG × Male (n=7) | 0.005 | |||
| Haplotypewise | AGA × TGA × Male (n=26) | 0.008 | 0.019 | ||
| TCG × TCG × Male (n=7) | 0.010 | ||||
| Genotypewise | SNP1ˆA/T × SNP2ˆC/G × Female (n=34) | 0.002 | |||
| SNP1ˆT/T × SNP2ˆC/C × Male (n=7) | 0.006 | ||||
| Allelewise | SNP1ˆA × SNP2ˆC × Female (n=34) | 0.004 | |||
| SNP1ˆT × SNP2ˆG × Female (n=152) | 0.007 |
“E-n”, scientific format of “10-n”; “×”, interaction between; E=Extraversion, A=Agreeableness, C=Conscienceness, and N=Neuroticism. The italic p values denote the sign of regression coefficient (β) is negative “-”; otherwise, positive “+”. Covariates of sex, age and ancestry are omitted in this table. The p values in grids are between 0.01 and 0.05; others are <0.01.EA student group is not listed in the table because no significant gene-personality association was found.