Table 1.
Effect of Ethanol on the Imax, K0.5 and Hill Coefficient for Gly-Sar Transport by hPepT1
| Imax (μA)* | K0.5 (mM) | Hill coefficient | |
|---|---|---|---|
| No ethanol | 0.69 ± 0.18 | 1.0 ± 0.3 | 1.3 ± 0.1 |
| 200 mM ethanol | 0.40 ± 0.12 | 0.9 ± 0.1 | 1.3 ± 0.1 |
Imax, K0.5, and Hill coefficient were calculated in the presence of 3 mM Gly-Sar and with and without 200 mM ethanol. Membrane potential was −110 mV and pH 5.5; n = 4 to 9.
p < 0.01 for no ethanol versus 200 mM ethanol.