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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Pharm Res. 2009 Aug 14;26(10):2358–2366. doi: 10.1007/s11095-009-9952-9

Table II.

Site-Directed Amino Acid Mutations at E595 and G594 in TMD 10 of hPEPT1 and R282 in TMD7

Mutation Codon change
E595D GAA to GAT
E595K GAA to AAG
E595R GAA to CGC
R282E AGG to GAG
E595K/R282E GAG-AAG to AGG-GAA
E595R/R282E GAG-GGC to AGG-GAA
G594A GGC to GCC
G594V GGC to GTC
C593A TGT to GCT
C593A/G594C TGTGGC to GCTTGC