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. Author manuscript; available in PMC: 2010 Dec 10.
Published in final edited form as: J Neuroimmunol. 2009 Oct 30;217(1-2):65–73. doi: 10.1016/j.jneuroim.2009.10.007

FIGURE 6.

FIGURE 6

Autoantibodies to DOR loops 1 and 3 are present in the sera of healthy individuals, SLE and HIV patients. Plates were coated with peptides corresponding to DOR and MOR loop 1 (L1) and 3 (L3) peptides. We tested the serum of 4 healthy individuals (N), 7 SLE patients and 13 HIV patients. Values reflect mean absorbance at 450nm ± s.d. of serum samples diluted 1 in 400. SLE serum samples show significantly lower binding to DOR loops 1 and 3 than normal sera (A, p<0.05). The converse is seen in binding to MOR loops, where SLE sera show higher binding than normal sera (B). HIV sera show significantly lower binding to DOR loops 1 and 3 than normal sera (C, p<0.001). The trend is reversed in binding to MOR loops 1 and 3 (D). Statistical significance was determined with a one-way analysis of variance, Bonferroni’s post-test was used to obtain p-values for the indicated pairwise comparisons.