Figure 1. Receiver operating characteristic curves for plasma drug concentration and the ability to detect drugs in the lungs for lamivudine (A) and efavirenz (B).
The areas under the receiver operating characteristic curves were 0.87 and 0.94 for 3TC and EFV, respectively (p < 0.0001 for both). The optimal plasma cut-offs suggested by the data are 178 ng/ml or less for 3TC and 2234 ng/ml or less for EFV.
EFV: Efavirenz; 3TC: Lamivudine.