. Author manuscript; available in PMC: 2011 Jan 1.

Published in final edited form as: HIV Ther. 2010 Mar 1;4(2):247–251. doi: 10.2217/hiv.10.5

Table 2.

Relationship between antiretroviral drugs and virologic failure in the lungs.

Drug class	Subjects (n)	Total failure rate in subjects on drug (%)	Total failure rate in subjects not on drug (%)	Failure rate and detectable drug in BAL fluid (%)	Failure rate and undetectable drug in BAL fluid (%)
NRTI	24	7/24 (29)	–	4/16 (25)	3/8 (38)
NNRTI	16	2/16 (13)^†	5/8 (63)	1/10 (10)	1/6 (17)
PI	9	4/9 (44)	3/15 (20)	3/5 (60)	1/4 (25)

^†

p = 0.02 for comparison of lung failure in those taking NNRTI versus those not taking NNRTI.

BAL: Bronchoalveolar lavage; NNRTI: Non-nucleoside/tide reverse transcriptase inhibitor; NRTI: Nucleoside/tide reverse transcriptase inhibitor; PI: Protease inhibitor.