Table 3.
Markersb | Distancec | SNP | Allele | All families |
EA Subset |
AA Subset |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Freq. | Z score | p value | Freq. | Z score | p value | Freq. | Z score | p value | |||||
rs742102 | 6,815 | C/T | T | 0.04 | 1.07 | 0.28 | 0.03 | 1.01 | 0.31 | 0.03 | N/A | N/A | |
rs17470454 | 1,032 | C/T | C | 0.95 | 0.67 | 0.5 | 0.93 | 0.63 | 0.53 | 0.98 | N/A | N/A | |
rs742106 | P1328 | 68,760 | C/T | T | 0.31 | 0.26 | 0.79 | 0.33 | 0.64 | 0.52 | 0.20 | −0.27 | 0.79 |
rs7758659 | 27,615 | G/A | G | 0.81 | 2.84 | 0.004 | 0.77 | 2.16 | 0.03 | 0.92 | 2.00 | 0.045 | |
rs2619539 | P1655 | 5,448 | C/G | G | 0.4 | 0.55 | 0.58 | 0.44 | 0.43 | 0.67 | 0.45 | 0.343 | 0.73 |
rs2743865 | 1,799 | C/T | T | 0.17 | 0.87 | 0.38 | 0.1 | 0.47 | 0.64 | 0.10 | 0.47 | 0.64 | |
rs3213207 | P1635 | 5,330 | A/G | A | 0.9 | 0.55 | 0.58 | 0.87 | 0.64 | 0.52 | 0.98 | N/A | N/A |
rs1011313 | P1325 | 20,217 | G/A | A | 0.09 | 0.14 | 0.89 | 0.1 | −0.31 | 0.76 | 0.02 | N/A | N/A |
rs2619522 | P1763 | 7,222 | T/G | T | 0.72 | 0.22 | 0.83 | 0.77 | 0.82 | 0.41 | 0.51 | −0.32 | 0.75 |
rs909706 | P1583 | 4,338 | A/G | G | 0.31 | 1.33 | 0.18 | 0.32 | 1.43 | 0.15 | 0.20 | −0.62 | 0.53 |
rs2619538 | SNP A | 3,452 | A/T | T | 0.43 | 0.58 | 0.56 | 0.42 | 1.09 | 0.27 | 0.37 | −0.61 | 0.54 |
rs742208 | N/A | T/C | C | 0.17 | 1.00 | 0.32 | 0.11 | −0.12 | 0.90 | 0.43 | 1.35 | 0.18 |
Results are shown in the whole sample, and EA and AA subsets. N/A = Not available due to the small number of AA families; SNP = nucleotide changes listed as major allele/minor allele. Allele nucleotides were converted to a unified format by ensuring they were from the minus strand. Nominal p value and associated allele are shown. Freq. = Frequency of the more often transmitted allele. Significant SNP (rs7758659) row is bold.
rs numbers are in the first column, and alias if any in the second column. Markers are in the order from the 3 to the 5 flanking regions.
Distance to next marker in base pairs (bp). The position for the first marker is nucleotide 15,624,612 in the UCSC May 2004 freeze of chromosome 6.