Table 4.
Adjusteda Mean Total IgG by Both Extent of Periodontal Disease (using Extent PD 5 mm) and by Extent Plaque Index Stratified by Quartile of Serum 8-Isoprostane
| |
Mean total IgG (ng/ml) |
|
|
|---|---|---|---|
| |
Mean (std err) |
|
|
| Serum quartiles of 8-isoprostaneb(n) | Low PD + low PI | High PD + high PI | p > |t|a |
| 1 (1,019) | 1,458.1 (58.2) | 2,309.6 (185.6) | 0.002 |
| 2 (1,048) | 1,297.4 (58.5) | 1,310.6 (149.4) | 0.93 |
| 3 (1,033) | 993.5 (60.2) | 1,259.8 (134.3) | 0.08 |
| 4 (980) | 849.3 (58.6) | 970.8 (177.5) | 0.19 |
| All (4,080) | 1,147.0 (30.7) | 1,465.4 (84.9) | 0.0007 |
a
Adjusted for race/center, gender, BMI, age, smoking, diabetes, hypertension, education, income, plaque, and serum LDL, HDL, and triglycerides.
b
8-Isoprostane effect on IgG significant for both High PD and Low PD groups at p < 0.0001.