Table 1.
Summary of Previous Reports on the Effect of Hypoxia on [ROS]i in Isolated Lungs, Pulmonary Arteries, and PASMCs
| Authors | Hypoxia | [ROS]i | Preparations | Detection methods | References |
|---|---|---|---|---|---|
| Archer et al. | Minutes | Decrease | Isolated rat lungs, pulmonary arteries, and PASMCs | AmplexRed, dihydroethidium, H2DCF, Lucigenin | (4; 50) |
| Jernigan et al. | Minutes Weeks | IncreaseIncrease | Isolated rat pulmonary arteries | H2DCF | (26; 27) |
| Killilea et al. | Minutes | Increase | Cultured rat PASMCs | H2DCF | (34) |
| Liu et al. | Minutes Weeks | Increase | Isolated porcine pulmonary arteries | Electron paramagnetic resonance, H2DCF, Lucigenin | (43) |
| Marshall et al. | Minutes | Increase | Cultured calf PASMCs | Lucigenin | (47) |
| Mehta et al. | Hours | Decrease | Cultured human PASMCs | Amplexred, Dihydroethidium, H2DCF, Lucigenin | (49) |
| Mittal et al. | Weeks | Increase | Isolated mouse pulmonary arteries | Dihydroethidium | (51) |
| Mohazzab and Wolin | Minutes | Decrease | Microsome-enriched fractions of calf pulmonary arteries | Lucigenin | (53) |
| Paddenberget al. | Minutes | Increase | Isolated mouse pulmonary arteries and cultured rabbit PASMCs | H2DCF | (61) |
| Rathore et al. | Minutes | Increase | Isolated mouse PASMCs | Cytochrome c reduction assay, H2DCF | (69; 70) |
| Wang et al. | Minutes | Increase | Isolated mouse PASMCs | H2DCF, lucigenin, RedoxSensor Red CC-1 | (97) |
| Wang et al. | Hours | Increase | Isolated rat pulmonary arteries | Dihydroethidium | (98) |
| Waypa et al. | Minutes | Increase | Cultured rat PASMCs | Fluorescence resonance energy transfer probe, H2DCF | (102; 103) |
| Wu et al. | Minutes Hours | DecreaseIncrease | Cultured human PASMCs | Dihydroethidium | (114) |