Fig. 3.
The Trojan-LTL peptide can be found near targets during IgG-dependent phagocytosis. Adherent neutrophils with internalized EA targets were labeled with the Trojan-LTL peptide and -AAA peptide. External EA were labeled with a secondary fluorescent anti-IgG (internalized EA are not labeled). The Trojan-LTL peptide accumulated at the site of EA binding before internalization (A and B); after internalization, it localized around the edge of EA-containing phagosomes (C and D). Cells stained with the control peptide exhibited no change in localization after phagocytosis (E and F). (x1800) (A–F, n=4; G and H, n=3)