Table 1.
Liposome compositions
Liposome # | Lipid formulation (Short description) | Composition (molar ratios) | Size (nm) | Osmolarity (mOsm) | References |
---|---|---|---|---|---|
I | SoyPC:Chol:DSPE-PEG2k (High cholesterol/long circulating) | 56:39:5 | 91 ±24 | 300 | [37] |
II | DPPC:SoyPC:Chol:DSPE-PEG2k (Temperature sensitive/long circulating) | 54:27:16:3 | 99 ±8 | 300 | [38] |
III | DPPC:lyso-PalmitoylPC:DSPE-PEG2k (Lysolipid temperature sensitive) | 86:10:4 | 95 ±25 | 300 | [39] |
IV | DPPC:lyso-PalmitoylPC:Ceramide-PEG2k (Ceramide-PEG version of III) | 86:10:4 | 101 ±22 | 300 | [39, 40] |
V | DPPC:DSPC:DSPE-PEG2k (Classical temperature sensitive) | 85.5:9.5:5 | 80 ±21 | 300 | [41] |
VI | DPPC:DSPC:Comb-PEG (Comb-PEG version of V) | 89.1:9.9:1 | 113 ±27 | 300 | [41, 42] |
VII, VIII, IX | DPPC:DSPC:Ceramide-PEG2k (Ceramide-PEG versions of V with varied osmolarity) | 85.5:9.5:5 | 99 ±14, 94 ±17, 92 ±20 | 300, 38, 10 | [40, 41] |