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. Author manuscript; available in PMC: 2010 Sep 15.
Published in final edited form as: Cancer Res. 2009 Sep 8;69(18):7165–7169. doi: 10.1158/0008-5472.CAN-09-1448

Fig. 1. miR-21 expression and regulation in CaP.

Fig. 1

A, Androgen-stimulated miR-21 expression. Northern blots of miR-21 dose-response (A, R1881). U6 used as a loading control. ’Fold-induction’ represents miR-21 relative to the non-stimulated state. B, miR-21 induction in additional AR-positive CaP cell lines. C, miPPR-21 Chromatin Immunoprecipitation. White = non-treated, Black = androgen-stimulated. Fold-enrichment represents AR immunoprecipitation relative to control antibody. ‘PSA E’: PSA Enhancer; ‘U’ control amplicon; ‘Neg’: non-conserved ARE. Mean ± SE from three independent measurements, *P<0.05, ***P<0.001 (t-student test). D, miR-21 in human CaP tumors. Fold-expression normalized to U6 by qRT-PCR. Mean ± SE, *P<0.05, ***P<0.001 (Two way ANOVA).

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