Table 1. Blood chemistry panel.
| YOUNG | AGED | ||
| CHOL (mg/dl) | CTRL | 119.4±19.7 | 124.4±10.1 |
| PIO | 85.4±8.0 * | 108.1±5.9 * | |
| TG (mg/dl) | CTRL | 291.2±45.5 | 184.2±44.1† |
| PIO | 141.1±21.4 ** | 88.4±8.7 **,† | |
| HDL (mg/dl) | CTRL | 70.3±7.8 | 83.2±5.8† |
| PIO | 62.5±5.6 | 76.7±3.6† | |
| INSULIN (ng/ml) | CTRL | 7.2±1.8 | 6.1±1.6 |
| PIO | 4.4±1.5 # | 4.2±1.3 # | |
| GLUCOSE (mg/dl) | CTRL | 112.1±4.9 | 102.4±6.6 |
| PIO | 109.5±8.2 | 101.4±8.1 | |
| ALT (IU/L) | CTRL | 48.9±4.9 | 51.0±2.7 |
| PIO | 37.5±3.2 | 47.7±4.6 |
Blood serum markers in control (CTRL) and PIO-treated (PIO) young and aged animals. Abbreviations: Cholesterol: CHOL; Triglycerides: TG; Alanine aminotransferase: ALT; High Density Lipoprotein: HDL.
*, **, and # indicate significant PIO effects (two-way ANOVA, p<0.05, p<0.001, and p<0.0005, respectively).
†
indicates significant aging effect (two-way ANOVA, p<0.05). Data represent mean ± SEM in 7–8 animals per group.