Table 1.

Mortality of patients with Parkinson’s disease by drug use

Treatment group	Person-time of observation (years)	No of deaths	Mortality ratio (95% CI)
			Adjusted for age and sex	Full adjustment*
Levodopa alone	9028.0	1124	1.00	1.00
Selegiline alone	1118.3	136	1.13 (0.95 to 1.35)	1.14 (0.95 to 1.36)
Selegiline with levodopa	4102.0	460	1.12 (1.00 to 1.25)	1.10 (0.98 to 1.23)
Selegiline alone or with levodopa	5220.3	596	1.12 (1.01 to 1.24)	1.11 (1.00 to 1.23)

^*Adjusted for age, sex, calendar year, smoking habit, regional health authority, diagnosis group, use of antidepressants (and specifically tricyclics and serotonin reuptake inhibitors), history of cerebrovascular disease, history of ischaemic heart disease, and incident or prevalent disease at entry to study.