Table 2. Determinants of risk of progression to HIV-infection or death (Multivariate Cox proportional Hazards model) at the CNPS hospital of Yaounde in Cameroon between 2004 and 2008.
N | HR** | 95% CI | P | HRa*** | 95% CI | P | |
Duration of treatment | |||||||
≥4 weeks before delivery | 288 | 1 | 1 | ||||
<4 weeks before delivery | 106 | 3.6 | 2.2–5.8 | 0.001 | 1.1 | 0.5–2.4 | 0.8 |
Treatment | |||||||
Regimen 1 (HAART) | 66 | 1 | 1 | ||||
Regimen 2 | 153 | 1.8 | 0.7–4.7 | 0.3 | 0.9 | 0.3–2.8 | 0.9 |
Regimen 3 | 94 | 2.7 | 0.9–7.1 | 0.05 | 1.3 | 0.4–3.7 | 0.7 |
Regimen 4 | 81 | 4.2 | 1.6–11 | 0.004 | 1.9 | 0.6–6.5 | 0.3 |
Feeding | |||||||
Formula feeding | 335 | 1 | 1 | ||||
Exclusive breastfeeding | 36 | 2.8 | 1.5–5.4 | 0.02 | 2.1 | 0.9–6.0 | 0.06 |
Mixed Feeding | 23 | 6.9 | 3.9–12.4 | 0.0001 | 8.7 | 3.6–20.6 | 0.001 |
Birth weight | |||||||
>2500 grams | 305 | 1 | 1 | ||||
≤2500 grams | 89 | 5.0 | 3.1–8.1 | 0.001 | 1.9 | 1.1–3.6 | 0.03 |
Prematurity * | |||||||
No | 332 | 1 | 1 | ||||
Yes | 62 | 4.3 | 2.6–7.0 | 0.0001 | 2.3 | 1.2–4.3 | 0.009 |
*(<37 weeks of gestation).
**Crude (Univariate).
***Adjusted (Multivariate).