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. 2010 Apr 29;5(4):e10402. doi: 10.1371/journal.pone.0010402

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Schartau et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) ΔBCD curves from 11 lens pairs where one lens was treated with dopamine and the other lens remained untreated are compared with ΔBCD curves from 10 lens pairs where one lens was treated with dopamine and the other lens with dopamine and the D1-antagonist SCH 23390. The curves are similar, indicating that the D1-antagonist abolished the effect of dopamine in the lens. The curves represent the mean ΔBCDs from 21 animals (Control: n = 11, D1 antagonist: n = 10). (B) The max-ΔBCDs and standard deviation. Both groups were similar with no statistically significant difference between them. This indicates that the D1-antagonist abolished the effect of dopamine. There was no significant (n.s) difference between the two groups (n = 21).