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. 2010 Apr 29;5(4):e10414. doi: 10.1371/journal.pone.0010414

Table 1. Neutralizing antibody response against FMDV C-S8c1, in mice, after vaccination with C-S8p260.

C-S8p260a Neutralization titer (PRN70)b
107 PFUs 30 days PIc 3 days PCd
Mouse #
1 2.0 1.8
2 2.0 2.0
3 2.4 2.2
4 2.1 1.9
5 1.3 1.5
6 1.7 1.8
7 0.4 1.9
8 1.7 1.8
9 2.7 2.4
10 1.9 1.9
103 PFUs
Mouse #
20 2.0 1.9
21 2.1 1.8
22 <0 1.8
23 1.7 1.8
24 1.4 2.4
25 1.6 1.8
26 1.4 1.8
27 0.6 1.1
28 1.4 1.5
29 1.7 1.8
a

Mice were vaccinated with 107 PFUs or 103 PFUs of C-S8p260, indicated for each group.

b

Neutralization titers are expressed as PRN70 (plaque-reduction neutralization titer 70): the reciprocal of the dilution of serum that causes neutralization of 70% of PFU.

c

30 days post-immunization.

d

3 days post-challenge with 104 PFUs of C-S8c1.