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Immunohistochemistry of CD77/Gb3 in the kidney of Fabry mice. (A) Wild-type mice unstained, (B) staining appeared in glomeruli and tubules of untreated Fabry mice, (C) stained tubules and glomeruli in Fabry mice treated with ERT, (D) No detection after 6 weeks in Fabry mice injected with 2 × 1012 particles of rAAV2/8-hAGA (×200).
