Figure 4. Validation of the corrected method for obtaining PRCs.

(A) PRCs of a model Purkinje cell, calculated using the corrected method in the stochastic model (black), in the deterministic model (green) and calculated using the traditional method in the stochastic model (red). Traces are shown at two different noise levels (increased CV indicated by dashed red and dashed black lines respectively). (B) PRC error, expressed as the integral of the differences between PRCs and their deterministic counterparts. The corrected method performs better than the traditional method in all cases, particularly at high CV.