Fig. 6.

a Mean (SE) percentage of phosphorylated (Ser 240/244) ribosomal S6 content of the gastrocnemius muscle, b mean (SE) atrogin-1 mRNA expression of the gastrocnemius muscle relative to GAPDH and c mean (SE) MuRF1 mRNA expression of the gastrocnemius muscle relative to GAPDH. White bars represent non-treated lox/lox mice, grey bars represent insulin-treated lox/lox mice and black bars represent insulin-treated MIRKO mice. *P < 0.05 indicates significant difference from untreated lox/lox mice