Table I.
mRNA expression of the Bcl-2 family and caspases during human pre-implantation embryo development.
| Ovary |
Oocyte |
Early embryo development stage |
|||||
|---|---|---|---|---|---|---|---|
| zygote | 2 cells | 8 cells | Blastocyst | ||||
| Bcl-2 family | |||||||
| Pro-apoptotic members: | Bak | +/− | n.d | + | + | + | + |
| Bax | +/− | +/− | + | + | + | + | |
| Bid | n.d | n.d | − | + | + | − | |
| Bad | n.d | n.d | + | + | + | + | |
| Anti-apoptotic members: | Bcl-2 | +/− | + | + | + | + | + |
| Bcl-xL | +/− | +/− | +/− | − | + | − | |
| Bcl-w | n.d | n.d | + | + | − | − | |
| Caspases | |||||||
| Caspase 2 | + | + | + | + | + | + | |
| Caspase 3 | +/− | + | + | +/− | + | + | |
This table shows the data of several publications and the contradictory results. +: detected, −: not detected, +/−: detected and not detected, n.d: not determined.