Table 1.
Group | Treatment (mg/kg; p.o.) | Body weight (g) | Water intake (ml/rat/day) | Food intake (g/rat/day) |
---|---|---|---|---|
I. Normal | Untreated | 170 ± 15 | 182 ± 22 | 11 ± 0.8 |
II. Control | Vehicle orally | 150 ± 12* | 184 ± 18ns | 13 ± 1.0** |
III. ATV | 10 | 165±13ns | 172 ± 16ns | 12 ± 0.7 ns |
IV. HCQ | 200 | 160 ±14ns | 180 ± 20ns | 12 ± 0.6 ns |
V. ATV + HCQ | 5 + 100 | 172 ±18ns | 165 ± 22ns | 11 ± 0.6** |
VI. ATV + HCQ | 10 + 200 | 182 ± 20** | 164 ± 15ns | 11 ± 1.0** |
Values are expressed as Mean ± S.D. (n= 6).
P<0.05;
P<0.01; ns P>0.05 (non-significant). Result of Group I was compared with Group II and Group II results with Group III, IV, V and VI. ATV- Atorvastatin, HCQ- Hydroxychloroquine