Table 2.
Group | Treatment (mg/kg; p.o.) | Plasma Glucose (mg/ dl) | % change from baseline | |
---|---|---|---|---|
Initial | Final | |||
I. Normal | Untreated | 082.1 ± 5.0 | 084.3 ± 7.2 | +03 |
II. Control | Vehicle orally | 305.2 ± 24.7 | 316.4 ± 23.6** | +04 |
III. ATV | 10 | 290.4 ± 20.2 | 239.8 ± 28.4** | −17 |
IV. HCQ | 200 | 302.3 ± 24.5 | 282.2 ± 21.3* | −07 |
V. ATV + HCQ | 5 + 100 | 296.6 ± 18.1 | 255.2 ± 19.4** | −14 |
VI. ATV + HCQ | 10 + 200 | 293.3 ± 20.8 | 231.7 ± 14.0** | −21 |
Values are expressed as Mean ± S.D. (n= 6). Statistical analysis was carried out by one way analysis of variance (ANOVA) followed by Students t-test.
P<0.05;
P<0.01: Result of Group I was compared with Group II and Group II results with Group III, IV, V and VI. ATV- Atorvastatin, HCQ- Hydroxychloroquine