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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Bioanalysis. 2010;2(3):519–541. doi: 10.4155/bio.09.188

Figure 2. Chemical and radiochemical doses used in AMS-based exploratory-IND and IND studies.

Figure 2

The radiochemical component typically ranges from 50 to 250 nCi (100 nCi is shown below). Note that all the studies should be referred to as lightly labeled studies, whereas only exploratory-IND studies should be referred to as microdosing studies.

AMS: Accelerator mass spectrometry; IND: Investigational new drug.