TABLE 3.

Cox proportional-hazards analysis of variables of 346 patients with periampullary cancer, undergoing pancreaticoduodenectomy

Variable	Univariate analysis	Multivariate analysis	Hazard ratio	Confidence interval
Site of primary	<0.001	0.322
Preoperative jaundice	0.096	0.078
Positive margins	0.023	0.373
Nodal metastasis	<0.001	0.014	1.53	(1.09, 2.16)
Size	0.068	0.717
Lymphovascular invasion	<0.001	0.130
Neural invasion	<0.001	<0.001	2.49	(1.56, 3.97)
Poor differentiation	0.6	0.6

Data represent P values. Perioperative mortality is excluded

The results on the two far left columns represent p-values from a Cox proportional hazards regression model. The results on the two far right columns represent the hazard ratios of the significant by multivariate analysis variables and their respective confidence intervals