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. Author manuscript; available in PMC: 2011 May 10.
Published in final edited form as: Virology. 2010 Feb 26;400(2):233–239. doi: 10.1016/j.virol.2010.01.034

Fig. 5.

Fig. 5

Decreased half-life of p130 in the cytoplasm in the presence of HPV 6 E7 and HPV 16 E7. (A) HFKs were infected as in Fig. 1. and treated with 0.25mM cycloheximide for the indicated times. Immunoblots of cytoplasmic extracts (top) and densitometry (bottom) from a representative experiment are shown. Cytoplasmic fractions were corrected for tubulin and are relative to LX. (B) Inhibition of p130 degradation by MG132. HFKs were infected as in A and treated with 0.25mM cycloheximide plus 50uM MG132 for the indicated times. Immunoblots of cytoplasmic extracts (top) and densitometry (bottom) from a representative experiment are shown.