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. Author manuscript; available in PMC: 2010 Apr 30.
Published in final edited form as: J Chromatogr A. 2008 Dec 6;1216(5):845–856. doi: 10.1016/j.chroma.2008.11.093

Fig. 2.

Fig. 2

Response surface graphs for the enantiomeric resolution of (±) BNP involving the three most significant factors in separation optimization using CCD. Factor which is not analyzed in each plot is held at its mean value (i.e., level 0 in Table 1). Sheath liquid and spray chamber parameters are the same as those in Fig. 1.