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. 2010 Apr 26;4:215–225. doi: 10.2147/opth.s9604

Figure 2.

Figure 2

Dual-targeted mechanism of action for besifloxacin.

Besifloxacin binds to and inhibits 2 enzymes that are essential for maintaining bacterial DNA in the proper conformation required for DNA transcription into RNA, DNA replication, and bacterial cell division.